Twitter Updates

    follow me on Twitter

    Monday, February 27, 2012

    Autism increases in the US

    Almost one percent of American children had an autism spectrum disorder (ASD) in a large CDC surveillance study whose lead author called the condition a "significant public health issue."

    Across 11 sites in the U.S., ASD prevalence in 2006 ranged from about one out of 80 children to one out of every 240 children, with an overall prevalence of one in 111 youngsters, according to a report by investigators from the CDC's Autism and Developmental Disorders Monitoring (ADDM) Network.

    Among 10 ADDM sites that reported data in both 2002 and 2006, there was an average 57% increase in ASD prevalence. No single factor could explain the rise, researchers said. Overall ASD prevalence was 4.5 times higher in boys than in girls: about one in every 70 boys and one in every 315 girls.

    From 2002 to 2006, prevalence increased 60% in boys and 48% in girls (P<0.001 for both).

    The American Academy of Pediatrics has recommended that all children be screened for autism when they are 18 and 24 months old which is especially important, as early recognition and treatment improves outcomes.

    ASD diagnosis was made at a slightly younger age in 2006 than in 2002, but it was still delayed to an average age of 53 months. That was so despite the fact that anywhere from 70% to 95% of children had developmental concerns noted in their records before age 3. Please remember, as with all our articles we provide information, not medical advice. For any treatment of your own medical condition you must visit your local doctor, with or without our article[s]. These articles are not to be taken as individual medical advice.

    Deepen your understanding of "medical malpractice"... www.MedMalBook.com

    For more health info and links visit the author's web site www.hookman.com

    Tuesday, February 7, 2012

    Abdominal surgeries riskier for older adults than previously thought

    About 2 million older adults undergo abdominal surgeries in the U.S. every year, a number that's expected to grow as the proportion of older adults increases rapidly: by 2020, one in six adults is expected to be older than 65, and 15% will be over 85.

    The patient records came from the Comprehensive Hospital Abstract Reporting System, a state-wide database that contains information on the age, sex, zip code, and billed charges of patients, as well as the codes for their diagnosis and procedures.

    The study focused on complications that occurred within 90 days of discharge and deaths within 90 days of hospital admission.

    After adjusting for various factors, including hospital volume and patient characteristics, the study found that the odds of early death after abdominal surgery increased considerably for each five-year increase in age beyond 65. These associations held for patients with cancer and other diagnoses, and for both elective and nonelective procedures (P<0.001).

    The likelihood of complications increased as patients aged beyond 65 years, with the researchers finding the following associations between age and complication frequency (trend test, P<0.001):

    65 to 69 years, 14.6%
    70 to 74 years, 16.1%
    75 to 79 years, 18.8%
    80 to 84 years, 19.9%
    85 to 89 years, 22.6%
    90 and older, 22.7%

    Similarly, older patients were at higher risk of mortality. Death rates by age group were (trend test, P<0.001):

    65 to 69 years, 2.5%
    70 to 74 years, 3.8%
    75 to 79 years, 6.0%
    80 to 84 years, 8.1%
    85 to 89 years, 12.6%
    90 and older, 16.7%
    http://www.blogger.com/img/blank.gif
    Massarweh N, et al "Impact of advancing age on abdominal surgical outcomes" Archttp://www.blogger.com/img/blank.gifh Surg 2009; 144: 1108-14.

    Please remember, as with all our articles we provide information, not medical advice. For any treatment of your own medical condition you must visit your local doctor, with or without our article[s]. These articles are not to be taken as individual medical advice.Please remember, as with all our articles we provide information, not medical advice. For any treatment of your own medical condition you must visit your local doctor, with or without our article[s]. These articles are not to be taken as individual medical advice.

    Deepen your understanding of "medical malpractice"... www.MedMalBook.com
    For more health info and links visit the author's web site www.hookman.com

    Tuesday, January 31, 2012

    RECURRENT CLOSTRIDIUM DIFFICILE INFECTION (CDI) ARE DIFFICULT TO TREAT

    Episodes of recurrent Clostridium difficile infection (CDI) are difficult to treat for several reasons. Foremost, data are lacking to support any particular treatment strategy. In addition, treatment of recurrent episodes is not always successful, and repeated, prolonged treatment is often necessary. Identification of subgroups at risk for recurrent CDI may aid in diagnosing and treating these patients. Two likely mechanistic factors increasing the risk of recurrent CDI are an inadequate immune response to C. difficile toxins and persistent disruption of the normal colonic flora. Important epidemiologic risk factors include advanced age, continuation of other antibiotics, and prolonged hospital stays. Current guidelines recommend that the first recurrent episode be treated with the same agent (i.e., metronidazole or vancomycin) used for the index episode. However, if the first recurrence is characterized as severe, vancomycin should be used. A reasonable strategy for managing a subsequent episode involves tapering followed by pulsed doses of vancomycin. Other potentially effective strategies for recurrent CDI include vancomycin with adjunctive treatments, such as Saccharomyces boulardii, rifaximin “chaser” therapy after vancomycin, nitazoxanide, fecal transplantation, and intravenous immunoglobulin. New treatment agents that are active against C. difficile, but spare critical components of the normal flora, may decrease the incidence of recurrent CDI.

    Please remember, as with all our articles we provide information, not medical advice. For any treatment of your own medical condition you must visit your local doctor, with or without our article[s]. These articles are not to be taken as individual medical advice.Please remember, as with all our articles we provide information, not medical advice. For any treatment of your own medical condition you must visit your local doctor, with or without our article[s]. These articles are not to be taken as individual medical advice.

    Deepen your understanding of "medical malpractice"... www.MedMalBook.com
    For more health info and links visit the author's web site www.hookman.com

    Sunday, January 15, 2012

    Best Treatment for Patients with Both Heart Disease and Diabetes? No Clear Answer

    For patients with both coronary artery disease and type 2 diabetes, outcomes are similar regardless of whether revascularization or medical therapy is used — and whether insulin sensitization or insulin provision is used — reports an industry-supported study published online in the New England Journal of Medicine.

    Researchers randomized some 2400 patients to either prompt revascularization or medical treatment, and to either insulin-sensitization or insulin-provision therapy. At 5 years, all-cause mortality did not differ between the revascularization and medical-therapy groups or between the insulin-sensitization and insulin-provision groups. Similarly, major cardiovascular events did not differ between groups.
    Patients were stratified before randomization according to type of revascularization, and patients in the CABG (but not PCI) group had fewer major cardiovascular events with revascularization but a similar mortality rate.

    Asked to comment, Journal Watch Cardiology Editor-in-Chief Dr. Harlan Krumholz said that the failure of the study to show clear superiority of revascularization and insulin sensitization "reinforces the need to incorporate the patient's preferences, values, and goals — and costs — into decisions about which strategy to pursue."

    Please remember, as with all our articles we provide information, not medical advice. For any treatment of your own medical condition you must visit your local doctor, with or without our article[s]. These articles are not to be taken as individual medical advice.

    Deepen your understanding of "medical malpractice"... www.MedMalBook.com
    For more health info and links visit the author's web site www.hookman.com

    Thursday, December 29, 2011

    Cancer Incidence And Mortality Continue To Decline

    Cancer incidence and mortality continue to decline, with the most dramatic decreases in lung, prostate, and colorectal cancers among men, and breast and colorectal cancers in women, according to the latest national report card.

    "Overall cancer incidence rates for all racial/ethnic groups combined decreased by 0.7% per year during 1999-2006 for both sexes combined, by 1.3% per year during 2000-2006 for men, and by 0.5% per year during 1998-2006 for women," authors from the American Cancer Society, the CDC, the National Cancer Institute, and the North American Association of Central Cancer Registries concluded. The report, was published online in the ACS journal, Cancer.

    There has been a decline in cancer death rates since the early 1990s and that trend appears to be durable.The decreases were slightly larger for men, who had declines of 1.5% per year during 1993-2001 and 2.0% per year during 2001-2006 compared with women, whose cancer death rates declined 0.8% per year during 1994-2002 and 1.5% per year during 2002-2006," the authors wrote.

    But the news was not all good. As men saw decreased rates of prostate, lung, oral, stomach, brain, and colorectal cancers, there was a concurrent increase in the cancers of the kidney, renal, liver, and esophagus -- as well as increases in leukemia, myeloma, and melanoma of the skin.

    For women the story was similar -- decreased rates of breast, colorectal, ovarian, cervical, uterine corpus, and oral cancers, but an uptick in lung, thyroid, pancreas, bladder, and kidney cancers, as well as increases in non-Hodgkin lymphoma, melanoma, and leukemia.

    Colorectal cancer [CRC] is a focus of this year's report, not a surprising choice because the news here is good: "CRC death rates have declined since 1984 in both men and women, with an accelerated rate of decline since 2002 (for men) and 2001 (for women)."

    And a "microsimulation model" suggests that death rates from colorectal cancer could be reduced by 36% over the next decade if "1995-2000 trends for risk factor prevalence, screening, and treatment continue."But the authors point out that increased obesity among younger Americans could derail this trend.

    Please remember, as with all our articles we provide information, not medical advice. For any treatment of your own medical condition you must visit your local doctor, with or without our article[s]. These articles are not to be taken as individual medical advice.

    Deepen your understanding of "medical malpractice"... www.MedMalBook.com
    For more health info and links visit the author's web site www.hookman.com

    Thursday, December 15, 2011

    Americans living longer than ever

    Americans living longer than ever. And every year that gets tacked on to the average life expectancy costs an extra trillion dollars in expenditures by Social Security and Medicare.

    Americans are living a record 77 years and 11 months on average...according to two studies that led researchers to suggest raising the retirement age." The first study, from the CDC's National Center for Health Statistics, found that in the "US in 2007, the latest year for which figures are available," the "0.76 percent death rate is the lowest ever," driven by "a decline in deaths from heart disease and other ailments." Meanwhile, a second study published Dec. 14 in the health journal Milbank Quarterly, found that "every year that gets tacked on to the average life expectancy costs an extra trillion dollars in expenditures by Social Security and Medicare."

            Overall, the 2007 data "show continued improvements in life expectancy for all Americans, although women are faring better than men, and whites fare better than other racial groups" by a "race differential" of about "4.6 years." But, even amid this progress, vast geographical discrepancies remain -- with people in southern states still facing higher death rates than those living in other parts of the country." And, "even though Americans can expect to live longer than their parents, life expectancy in the" US "is still lower than in many other industrialized countries, including Canada and Japan. Even so, the "dramatic improvements in the health of Americans over the last 20 years" will "have unforeseen effects on the country. The Social Security and Medicare "programs weren't designed to support people for that long."

    Please remember, as with all our articles we provide information, not medical advice. For any treatment of your own medical condition you must visit your local doctor, with or without our article[s]. These articles are not to be taken as individual medical advice.

    Deepen your understanding of "medical malpractice"... www.MedMalBook.com
    For more health info and links visit the author's web site www.hookman.com

    Wednesday, November 30, 2011

    Maternal Use of Sertaline, Citalopram Linked to Septal Heart Defects in Offspring

    Women who use the antidepressants sertraline (Zoloft) or citalopram (Celexa) early in pregnancy face increased risk for septal heart defects in their offspring, BMJ reports online.

    Researchers examined data on more than 490,000 infants born in Denmark between 1996 and 2003. They found that women who filled prescriptions for sertraline and citalopram (but not other SSRIs) during their first trimester were significantly more likely to have children with septal heart defects (but not other malformations) than those who didn't use SSRIs (odds ratios: 3.2 and 2.5, respectively).
    The authors and an editorialist (both with ties to SSRI manufacturers) note that the absolute risks for septal heart defects were low: 0.9% in children exposed to at least one SSRI and 2.1% in those exposed to more than one.
    The editorialist concludes: "Clinicians and patients need to balance the small risks associated with SSRIs against those associated with undertreatment or no treatment."

    Please remember, as with all our articles we provide information, not medical advice. For any treatment of your own medical condition you must visit your local doctor, with or without our article[s]. These articles are not to be taken as individual medical advice.

    Deepen your understanding of "medical malpractice"... www.MedMalBook.com
    For more health info and links visit the author's web site www.hookman.com