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    Tuesday, October 5, 2010


    Most people know about the two most common idiopathic [cause not known] inflammatory bowel disorders—Crohn’s disease and ulcerative colitis. There are also two other inflammatory bowel diseases that most people don’t know about.
    That is collagenous colitis and lymphocytic colitis. The diagnosis is made by biopsy through a colonoscope. The treatment is a type of steroid called Budesonide.
    Results of studies show that Histologic remission was observed in 73% of patients given budesonide compared with 31% given placebo (P = .030). During a mean follow-up period of 14 months, 15 patients (44.1%) experienced a clinical relapse (after a mean of 2 months); 8 of the relapsing patients were retreated with and responded again to budesonide. Budesonide effectively induces clinical remission in patients with lymphocytic colitis and significantly improves histology results after 6 weeks.
    Clinical relapses occur but can be treated again successfully with budesonide.

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