Low-Carb Diet Improves Symptoms & Quality of Life in Diarrhea predominant IBS

Data published in Clinical Gastroenterology and Hepatology suggest that a very low-carbohydrate diet (VLCD) provides adequate relief and improves abdominal pain, stool habits and quality of life in IBS-D.

Patients with IBS-D anecdotally report symptom improvement after initiating a VLCD; this study prospectively evaluated a VLCD in IBS-D. Participants with moderate to severe IBS-D were provided a two-week standard diet, then four weeks of a VLCD (20 g carbohydrates/d). A responder was defined as having adequate relief of gastrointestinal symptoms for two or more weeks during the VLCD. Changes in abdominal pain, stool habits and quality of life also were measured.
Of the 17 participants enrolled, 13 completed the study and all met the responder definition, with 10 reporting adequate relief for all four VLCD weeks. Stool frequency decreased and stool consistency improved from diarrheal to normal form. Pain scores and quality-of-life measures significantly improved (outcomes were independent of weight loss).

From Clinical Gastroenterology and Hepatology; 2009: 7(6): 706-708.e1

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