COMMONLY USED DRUGS THAT INCREASE PHOTOSENSITIVITY

You surely know that this is summer the great season of the year of cook-outs, the beach and lots of sun. But you should also be aware of the following medicaltions that you may be taking that increases photosensitivity—and take extra precautions if you fit in this picture.

Analgesic Agents
NSAIDs: celecoxib (Celebrex), diclofenac (Voltaren, Cataflam), diflunisal (Dolobid), etodolac (Lodine), ibuprofen (Motrin), indomethacin, ketoprofen (Orudis), mefenamic acid (Ponstel), meloxicam (Mobic), nabumetone (Relafen), naproxen (Anaprox), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril)
Other: cyclobenzaprine (Flexeril), dantrolene (Dantrium), sumatriptan (Imitrex)

Antibiotics
Fluoroquinolones: ciprofloxacin (Cipro), gemifloxacin (Factive), levofloxacin (Levaquin), lomefloxacin (Maxaquin), moxifloxacin (Avelox), norfloxacin (Noroxin), ofloxacin (Floxin) Tetracyclines: demeclocycline (Declomycin), doxycycline (Vibramycin), minocycline (Minocin), oxytetracycline (Terramycin), tetracycline (Achromycin), tigecycline (Tygacil) Other: azithromycin (Zithromax), capreomycin (Capastat), ceftazidime (Fortaz), cefazolin (Ancef), cycloserine (Seromycin), dapsone, gentamicin, griseofulvin, ethionamide (Trecator), isoniazid (Nydrazid), metronidazole (Flagyl), nalidixic acid (NegGram), pyrazinamide, sulfamethoxazole/trimethoprim (Bactrim), sulfasalazine (Azulfidine), sulfisoxazole (Gantrisin)

Antidepressants
Tricyclic Antidepressants: amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Tofranil), maprotiline (Ludiomil), nortriptyline (Pamelor), protriptyline (Vivactil), trimipramine (Surmontil)
Selective serotonin reuptake inhibitors: citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft)
Antidepressant, Other: bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), venlafaxine (Effexor)

Antidiabetic Agents
Sulfonylureas: acetohexamide (Dymelor), chlorpropamide (Diabinese), glimepiride (Amaryl), glipizide (Glucotrol), glyburide (DiaBeta, Micronase), tolazamide (Tolinase), tolbutamide (Orinase)

Antihistamines
cetirizine (Zyrtec), cyproheptadine (Periactin), diphenhydramine (Benadryl), loratadine (Claritin), promethazine (Phenergan)

Antiplatelet
clopidogrel (Plavix)

Cardiovascular
Thiazide diuretics: bendroflumethiazide (Corzide), chlorthalidone (Thalitone), hydrochlorothiazide (Microzide), hydroflumethiazide (Diucardin), indapamide (Lozol), methyclothiazide (Enduron), metolazone (Zaroxolyn) Diuretics, Other: bumetanide (Bumex), furosemide (Lasix), triamterene (Dyrenium)
Antihypertensives: amlodipine (Norvasc), captopril (Capoten), diltiazem (Cardizem, Tiazac), enalapril (Vasotec), hydralazine, labetalol, minoxidil, nifedipine (Procardia), sotalol (Betapace) Statins: atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor), pravastatin (Pravachol), simvastatin (Zocor)
Other: acetazolamide, amiodarone (Cordarone, Pacerone), fenofibrate (Tricor), methyldopa, quinidine

Vitamins
pyridoxine (vitamin B6), vitamin A

REFERENCES:
Dukes MNG, Aronson JK. Meyler's side effects of drugs. 14th ed. Amsterdam: Elsevier; 2000.
Moore DE. Drug-induced cutaneous photosensitivity. Drug Saf 2002;25:345-72.
Allen JE. Drug-induced photosensitivity. Clin Pharm 1993;12:580-7
Pharmacist's Letter/Prescriber's Letter 2009;25(6):250606.


Please remember, as with all our articles we provide information, not medical advice.
For any treatment of your own medical condition you must visit your local doctor, with or without our article[s]. These articles are not to be taken as individual medical advice.

* Tune in tomorrow for PART I of II DETRIMENTAL EFFECTS OF ASPIRIN

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